Studies on the dissociation of botulinum neurotoxin type A complexes (ENG)

BoNT A toxin complexes have evolved to quickly respond to specific environmental changes by efficient release of the neurotoxin. During pharmaceutical production and reconstitution of BoNT A products, the same principles effect the quantitative dissociation of 900 kDa complexes and release of free neurotoxin prior to injection into target tissues. Copyright © 2011 Elsevier Ltd. All rights reserved.
Автор:  Eisele KH, Fink K, Vey M, Taylor HV.
Год публикации:  2010
Файл:  Загрузить