Prospective analysis of neutralising antibody titres in secondary non-responders under continuous treatment with a botulinumtoxin type A preparation free of complexing proteins— a single cohort 4-year follow-up study (ENG)

Following a transient increase in the first 24 months under incobotulinumtoxinA treatment in some patients, NABTs declined well below the initial titre in the majority of patients. Test assay results were negative in most of the patients followed for more than 36 months. NABTs seemed to decline into the negative detection range as rapidly under incobotulinumtoxinA treatment as after cessation of botulinum neurotoxin therapy.
Автор:  Harald Hefter, Christian Hartmann, Ulrike Kahlen, Marek Moll, Hans Bigalke
Год публикации:  2012
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